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本文介绍了二甘醇单甲醚和二甘醇双甲醚对昆明种小鼠和Wistar大鼠的急性毒性.二甘醇单甲醚口服LD_(50)值昆明种小鼠为8.5ml/kg,Wistar大鼠为8.2ml/kg;二甘醇双甲醚口服LD_(50)值昆明种小鼠为5.8ml/kg.二甘醇单甲醚和二甘醇双甲醚昆明种小鼠吸入急性毒性,在过饱和蒸气浓度下,染毒4小时,两周内动物未出现死亡.二甘醇单甲醚和二甘醇双甲醚对兔皮肤均有轻度刺激性,对兔眼粘膜刺激性均呈阳性反应,后者较前者刺激性强.
This article describes the acute toxicity of diethylene glycol monomethyl ether and diethylene glycol dimethyl ether to Kunming mice and Wistar rats oral diethylene glycol monomethyl ether LD_ (50) value of Kunming mice was 8.5ml / kg , Wistar rats was 8.2ml / kg; diethylene glycol methyl ether oral LD_ (50) value of Kunming mice was 5.8ml / kg. Diethylene glycol monomethyl ether and diethylene glycol diacetate Kunming mice inhaled Acute toxicity, in the saturated steam concentration, exposure to four hours, two weeks did not die animals diethylene glycol monomethyl ether and diethylene glycol dimethyl ether on the skin of rabbits were slightly irritating to the rabbit eye mucosa Irritation were positive, the latter irritating than the former.