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将３种类型１５３Ｓｍ一树脂微球（１５３Ｓｍ一ＲＴＭＳ）穿刺注入３组家兔肝脏局部，用ＳＰＥＣＴ分别于注射后１ｈ、２ｄ、２ｄ、３ｄ、４ｄ．５ｄ拍摄全身平面影像．在不同像上勾画ＲＯＩ，计算总流失率（Ｌ％）和脏摄取率（Ｕ％）．结果表明，未处理型和明胶处理型的１５３ＳＳｍ一ＲＴＭＳ的总流失率（Ｌ％）和在各脏器的摄取率（Ｕ％）皆随时间的推移逐渐升高，其中全身骨摄取率（Ｕ％）５天后可高达２０％，而包被处理型１５３Ｓｍ—ＲＴＭＳ在各脏器摄取率（Ｕ％）只轻度增加，总流失率（Ｌ％）变化也不大，有效半衰期也最接按１５３Ｓｍ的物理半衰期，说明较大的树指微球（７５μ）经过包被处理后不易分解和弥散，稳定性较强。
Three types of 153Sm-resin microspheres (153Sm-RTMS) were punctured and injected into the liver of three groups of rabbits. SPECT was performed at 1h, 2d, 2d, 3d, 4d after injection. 5d shoot whole body image. The ROI was plotted on different images and the total loss (L%) and dirty intake (U%) were calculated. The results showed that the total loss rate (L%) and the uptake rate (U%) in untreated and gelatin-treated 153SSm-RTMS all increased gradually with the passage of time. The rate of whole body bone uptake (U %) Increased up to 20% after 5 days while the uptake rate (U%) of the coated 153Sm-RTMS in each organ increased only slightly, the total loss rate (L%) did not change much, and the effective half-life 153Sm physical half-life, indicating that the larger tree refers to the microspheres (75μ) after coating is not easy to break down and dispersion, strong stability.