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目的探讨原发性痛风的临床表现、诊断标准、治疗与转归以提高对该病的认识。方法对114例原发性痛风进行回顾性分析。结果 114例首次发病于骨关节者107例,尿路结石7例;114原发性痛风患者,下肢关节受累89例(78.1%),上肢关节受累47例(41.2%);114例痛风患者均伴有不同程度的尿酸增高,男>420μmol/L,女>350μmol/L;经控制饮食、多饮水,急性期给予秋水仙碱治疗,间歇期给予别嘌醇治疗,疗效满意。结论原发性痛风发病率明显升高,危害性加大,应引起临床医生的重视,同时患者应在临床医生的指导下合理应用痛风膳食并长期坚持服降尿酸药,有效地治疗原发性痛风。
Objective To investigate the clinical manifestations, diagnostic criteria, treatment and prognosis of primary gout to improve their understanding of the disease. Methods 114 cases of primary gout were retrospectively analyzed. Results Of the 114 patients with primary gout, 89 cases (78.1%) had lower extremity joint involvement and 47 (41.2%) patients had upper limb joint involvement; 114 patients with gout Accompanied by varying degrees of increased uric acid, male> 420μmol / L, female> 350μmol / L; controlled diet, drinking water, acute colchicine treatment, intermittent allopurinol treatment, the effect is satisfactory. Conclusions The incidence of primary gout is obviously increased and its harmfulness is increased, which should be paid more attention to by clinicians. At the same time, patients should be given gout meal rationally under the guidance of clinicians and insist on taking uric acid for a long time to effectively treat primary gout.