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应用放射免疫方法测定、研究了健康新生儿33例和窒息新生儿56例的血浆ET－1和6－KetoPGF-1（PGI2稳定代谢产物）水平的动态变化。结果表明：（1）≤2天健康新生儿两种血浆浓度均显著高于生后8～9天组。（2）窒息新生儿两种血浆水平显著升高，与窒息的严重程度及窒息造成机体损害的严重度呈正相关；血浆ET－1与PGI。处于动态平衡，表现了内皮细胞水平的自身调节。（3）重庆HIE血浆ET－1下降甚缓慢，与PGI。处于失衡状态。本文讨论了ET－1与其相桔抗的PGI2。在国产期窒息病理生理过程中的作用。
The radioimmunoassay method was used to study the dynamic changes of plasma ET-1 and 6-KetoPGF-1 (stable metabolites of PGI2) in 33 normal healthy neonates and 56 asphyxia neonates. The results showed that: (1) Both plasma concentrations of healthy neonates less than 2 days were significantly higher than those of 8-9 days after birth. (2) Neonatal asphyxia both plasma levels increased significantly, and the severity of asphyxia and asphyxia caused by the severity of the damage was positively correlated; plasma ET-1 and PGI. In a homeostasis, endothelial cells display their own level of regulation. (3) Chongqing HIE plasma ET-1 decreased very slowly, and PGI. In an imbalance This article discusses PGI2 against which ET-1 is antagonistic. Role in the Pathophysiology of Asphyxia during Homeopathy.