大鼠背部２０％体表面积接触沸水２０ｓ，形成Ⅲ度烫伤后，延髓孤束核推挽灌流液中β－内啡肽免疫活性物质的含量显著升高，在烫后１、４ｈ两次达到峰值。烫后立即向弧束核微量注射０．４μｌβ－内啡肽抗血清（滴度１：３００００），可在一定程度上改善心功能指标，延缓血压和心率的下降，但未能延长动物的存活时间。提示孤束核的β－内啡肽在烫伤休克的病理过程中起作用，其含量的过量升高有抑制心血管功能的作用，从而不利于烫伤休克的恢复。 After 20% of the body surface area of ​​the rats contacted the boiling water for 20s, the level of β-endorphin immunoreactive substance in the medulla oblongata solo-perfusion fluid after the third-degree scald was significantly increased, reaching the peak twice at 1,4h . Micro-injection of 0.4 μl β-endorphin antiserum (titer 1: 30000) to the nucleus of arcuate nucleus immediately after ironing may improve cardiac function to a certain extent, retard the decline of blood pressure and heart rate, but fail to prolong the survival of animals time. It is suggested that β-endorphin of nucleus tractus solitarius plays a role in the pathological process of scald shock. Excessive increase of its content can inhibit the function of cardiovascular system, which is not conducive to the recovery of scald shock.