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目的观察苯磺酸氨氯地平降压疗效及不良反应。方法选择91例14d未用任何降压药物的患者,给苯磺酸氨氯地平5～10mg/d,上午1次口服,每周1次上午复诊,由专人使用固定台式血压计测坐位血压3次,取其平均值,同时记录心率、自觉症状及不良反应,共观察8周。结果治疗4、8周后舒张压和收缩压的降低均有显著差异,而治疗前后心率无显著差异,治疗8周后总有效率为82.63%,不良反应率为11.40%。结论苯磺酸氨氯地平治疗轻中度高血压病里疗效确切,不良反应轻微。
Objective To observe the antihypertensive effects and adverse reactions of amlodipine besylate. Methods 91 cases of patients without any antihypertensive drugs on the 14th day were treated with amlodipine besylate 5 ~ 10mg / d, orally 1 am and weekly morning ambulatory referral. Blood pressure was measured by hand using a fixed bench type blood pressure monitor Times, whichever average, while recording heart rate, symptoms and adverse reactions, observed a total of 8 weeks. Results After 4 and 8 weeks of treatment, the decrease of diastolic blood pressure and systolic blood pressure were significantly different. There was no significant difference in heart rate before and after treatment. After 8 weeks of treatment, the total effective rate was 82.63% and the adverse reaction rate was 11.40%. Conclusion Amlodipine besylate is effective in treating mild-to-moderate essential hypertension with mild adverse reactions.