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目的:观察珍菊降压片治疗高血压的疗效。方法:将原发性高血压患者60例随机分为治疗组(珍菊降压片)32例与对照组(珍菊降压片+苯磺酸氨氯地平)28例,经8周治疗后,观察两组治疗前后动态血压、血压变异性。结果:治疗后,两组患者的收缩压和舒张压均有明显改变,且与治疗前相比差异均有统计学意义(P<0.05)。治疗组和对照组收缩压下降幅度分别为10.3%、11.4%,两组比较差异无统计学意义(P>0.05);舒张压下降幅度分别为17.7%、18.3%,两组比较差异无统计学意义(P>0.05)。治疗组和对照组总有效率分别为93.94%、96.3%,两组比较差异无统计学意义(P>0.05)。两组患者均未见严重不良反应。结论:珍菊降压片治疗轻中度高血压的临床疗效较好,且不良反应少,值得临床推广应用。
Objective: To observe the efficacy of Zhenju Jiangya Tablet in the treatment of hypertension. Methods: Sixty patients with essential hypertension were randomly divided into treatment group (Zhenju antihypertensive tablets) 32 cases and control group (Zhenju antihypertensive tablets + amlodipine besylate) 28 cases, after 8 weeks of treatment The changes of ambulatory blood pressure and blood pressure before and after treatment were observed. Results: After treatment, the systolic and diastolic pressures of both groups were significantly changed, and the differences were statistically significant compared with those before treatment (P <0.05). The decrease of systolic blood pressure was 10.3% in treatment group and 11.4% in control group, respectively. There was no significant difference between the two groups (P> 0.05). The decrease of diastolic blood pressure was 17.7% and 18.3% respectively Significance (P> 0.05). The total effective rate of the treatment group and the control group were 93.94% and 96.3% respectively, with no significant difference between the two groups (P> 0.05). No serious adverse reactions were seen in both groups. Conclusion: Zhenju antihypertensive tablets for the treatment of mild to moderate hypertension clinical efficacy is good, and less adverse reactions, it is worthy of clinical application.