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目的了解丰台区不同健康人群的麻疹免疫水平,以制定相应疫苗免疫策略。方法采用随机抽样方法抽取10个行政村/居共计220名健康人群调查人口学信息和免疫史,采用酶联免疫吸附试验检测麻疹Ig G抗体。结果丰台区健康人群麻疹抗体总阳性率和平均抗体浓度分别为86.8%和2 089.94 IU/L,不同年龄组间、不同免疫史人群、不同职业人群的麻疹抗体阳性率和平均抗体浓度均有统计学差异,χ2值分别为84.897,61.5,25.122,P<0.001;F值分别为22.308,42.1,4.576,P<0.001。结论在提高常规免疫及时性的基础上,大年龄组人群麻疹疫苗接种应覆盖到本市户籍,尤其对育龄妇女、干部职员等一些重点人群加强宣教,开展强化免疫活动,以达到减少易感人群,控制麻疹疫情的目标。
Objective To understand the level of measles immunity in different healthy population in Fengtai District in order to formulate the corresponding vaccine immunization strategy. Methods A total of 220 healthy population of 10 administrative villages / houses were selected to investigate the demographic information and immunization history using random sampling method. The Ig G antibody of measles was detected by enzyme linked immunosorbent assay. Results The total positive rate and average antibody concentration of measles antibody in healthy population in Fengtai district were 86.8% and 2 089.94 IU / L, respectively. The positive rate of measles antibody and the average antibody concentration of different occupational groups in different age groups, Χ2 values were 84.897,61.5,25.122, P <0.001; F values were 22.308,42.1,4.576, P <0.001. Conclusion On the basis of improving the timeliness of routine immunization, the vaccination of measles in the population of older age should cover the household register in this Municipality. In particular, some key population groups such as women of childbearing age, cadres and staff should strengthen their missionary activities and intensify their immunization activities so as to reduce the susceptible population , Control the measles outbreak target.