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目的观察呼吸机无创间歇正压通气治疗慢性阻塞性肺疾病(COPD)合并呼吸衰竭(Ⅱ型)的临床疗效。方法 60例COPD合并呼吸衰竭(Ⅱ型)患者,随机分为观察组和对照组,各30例。对照组给予常规西药和鼻导管吸氧;观察组给予双水平气道正压通气(BiPAP)呼吸机无创间歇正压通气治疗。观察指标包括动脉血气分析指标及成功脱机患者的无创通气时间。结果治疗后两组患者的动脉血气分析pH值和PaO2均较治疗前明显升高(P<0.05),PaCO2明显下降,差异有统计学意义(P<0.05);观察组在改善PaO2和PaCO2方面明显优于对照组,差异有统计学意义(P<0.05)。结论呼吸机无创间歇正压通气救治COPD合并呼吸衰竭(Ⅱ型)可改善患者的通换气功能,缩短呼吸机通气时间,疗效确切,值得临床推广使用。
Objective To observe the clinical effect of ventilator noninvasive intermittent positive pressure ventilation on chronic obstructive pulmonary disease (COPD) with respiratory failure (type Ⅱ). Methods Sixty COPD patients with respiratory failure (type Ⅱ) were randomly divided into observation group and control group, with 30 cases in each group. The control group was given conventional Western medicine and nasal catheter oxygen inhalation. The observation group was given bi-level positive airway pressure (BiPAP) noninvasive intermittent positive pressure ventilation. Observations included arterial blood gas analysis indicators and successful non-invasive ventilation in patients with non-invasive time. Results After treatment, arterial blood gas analysis showed that both PaO2 and PaO2 were significantly increased (P <0.05) and PaCO2 was significantly decreased in the two groups (P <0.05). The PaO2 and PaCO2 in the observation group were significantly improved Obviously superior to the control group, the difference was statistically significant (P <0.05). Conclusion Ventilator noninvasive intermittent positive pressure ventilation for COPD with respiratory failure (type Ⅱ) can improve the patient’s ventilation function, shorten ventilator ventilation time, the exact effect, worthy of clinical promotion and use.