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目的:探讨脑梗死康复期并发肺部感染的常见危险因素,为其临床的防治工作提供可参考依据。方法:共纳入120例入住我院神经内科的脑梗死且处于康复期患者,采用统一的调查表详细记录所有患者的病史及相关信息。同时根据其是否发生肺部感染分为2组,应用多因素回归分析进行多因素分析。结果:120例脑梗死康复期患者中有20例患者发生肺部感染,感染发生率为16.7%;感染组患者患糖尿病14例,占70.0%,患冠心病15例,占75.0%,患COPD病10例,占50.0%,NIHSS评分(10.1±2.2),明显高于非感染组患者患糖尿病45例,占45.0%,患冠心病50例,占50.0%,患COPD病25例,占25.0%,NIHSS评分(6.8±1.3),2组间差异比较存在统计学意义(P<0.05);多因素分析显示,既往存在糖尿病史、COPD病史及NIHSS评分高为脑梗死康复期并发肺部感染的独立危险因素(P<0.05)。结论:脑梗死康复期并发肺部感染的发生与既往存在糖尿病史、COPD病史及脑梗死的严重程度存在密切相关性,是其发生的独立危险因素。因此有上述危险因素的脑梗死患者,即使康复期亦应该注意肺部感染的预防。
Objective: To explore the common risk factors of pulmonary infection in convalescent cerebral infarction and to provide reference for its clinical prevention and treatment. Methods: A total of 120 admitted to our hospital neurology department of cerebral infarction and in convalescent patients, using a unified questionnaire detailed records of all patients history and related information. At the same time, it was divided into two groups according to whether there was pulmonary infection or not. Multivariate regression analysis was used to analyze multivariate analysis. RESULTS: Twenty cases of 120 patients with cerebral infarction recovered from pulmonary infection, the incidence of infection was 16.7%. In the infected group, 14 cases were diabetes (70.0%), 15 cases were coronary heart disease (75.0%), and COPD The NIHSS score (10.1 ± 2.2) was significantly higher in 45 patients (45.0%) than in non-infected patients (50.0%), 50.0% (50.0%) of patients had coronary heart disease, 25 patients had COPD disease (25.0%) %, And NIHSS score (6.8 ± 1.3). There was significant difference between the two groups (P <0.05). Multivariate analysis showed that there was a history of diabetes mellitus, history of COPD and high NIHSS score in patients with concomitant pulmonary infection Independent risk factors (P <0.05). Conclusions: The incidence of pulmonary infection during convalescence of cerebral infarction is closely related to the history of previous diabetes, the history of COPD and the severity of cerebral infarction, and is an independent risk factor for its occurrence. Therefore, patients with cerebral infarction with the above risk factors should pay attention to the prevention of pulmonary infection even during the rehabilitation period.