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病理学是一门有丰富理论又密切联系临床的科学。近年来,随着生物化学、细胞化学、分子生物学、免疫学等学科的发展,促进病理学各领域有了更大的飞跃。一、电镜技术电镜作为一项新技术,从本世纪三十年代问世以来,已在医学生物学科研领域广为利用,而病理方面仅在近20年才开始用于各器官系统疾病的病理诊断。肿瘤病理诊断:在肿瘤病理诊断中电镜应用较广,尤其对下列肿瘤有所裨益。1.通过对细胞质的神经内分泌颗粒检查,可根据数量、形态、大小、分布等特征加以区别。如类癌,颗粒为圆形或卵圆形,直径80nm~300nm,其中肺雀麦细胞癌的前肠类癌颗粒大小一致,小而圆,直径平均185nm,中肠类癌颗粒大而多形,直径平均230nm,
Pathology is a science rich in theory and closely linked to clinical science. In recent years, with the development of biochemistry, cell chemistry, molecular biology, immunology, and other disciplines, the promotion of pathology has made a greater leap in all areas. 1. Electron microscopy As a new technology, electron microscopy has been widely used in scientific research of medical biology since its inception in the 1930s, but pathology has only begun to be used for the pathological diagnosis of diseases of various organ systems in the last 20 years. . Diagnosis of tumor pathology: In the pathological diagnosis of tumors, electron microscopy is widely used, especially for the following tumors. 1. By examining cytoplasmic neuroendocrine granules, they can be distinguished based on the number, morphology, size, distribution and other characteristics. Such as carcinoid, the particles are round or oval, diameter 80nm ~ 300nm, of which the pulmanary bile cell carcinoma of the foregut carcinoid particles of the same size, small and round, an average diameter of 185nm, large and polymorphic midgut carcinoid particles , the average diameter of 230nm,