可逆性后部白质病变综合征(RPLS)是指:大部分后大脑半球发生可逆的、对称性的脑白质水肿,癫痫是该病的标志性临床特征。恶性高血压、子痫、使用细胞毒性药物及免疫抑制剂时发生此病多有报道。医院收治血栓性血小板减少性紫癜(TTP)引起可逆性后部白质病变综合征1例,报道如下。1病例资料患者,男,17岁,主因皮疹、发热、关节痛1个月,意识障碍、尿少1天入院。既往否认高血压病史;患者于2016年3月 Reversible posterior white matter syndrome (RPLS) refers to: most of the posterior hemisphere reversible symmetry of white matter edema, epilepsy is a landmark clinical features of the disease. Malignant hypertension, eclampsia, the use of cytotoxic drugs and immunosuppressive agents occur when the disease has been reported. Hospital treatment of thrombotic thrombocytopenic purpura (TTP) caused reversible posterior white matter syndrome in 1 case, reported as follows. 1 case data patients, male, 17 years old, mainly due to rash, fever, arthralgia for 1 month, disturbance of consciousness, less urine 1 day admission. Previously denied a history of hypertension; patients in March 2016