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目的 研究重症高血压脑出血后早期鼻饲生大黄粉对防治上消化道出血的作用。方法 选择GCS4～ 8分重症高血压脑出血患者 82例 ,随机选 41例 (实验组 )发病后早期 (2 4～ 48h)鼻饲生大黄粉 ,另 41例 (对照组 )未予生大黄粉治疗。所有患者其他治疗措施均基本相同。结果 37例患者出现上消化道出血。其中实验组 13例 ,有12例上消化道出血治愈 ,治愈时间 (7.3± 2 .4)d(n =12 ) ;对照组 2 4例 ,有 14例上消化道出血治愈 ,治愈时间 (13.1±3.2 )d(n =14 )。实验组上消化道出血率和上消化道出血治愈平均时间均显著低于对照组 (P <0 .0 5 ) ,而上消化首出血治愈率显著高于对照组 (P <0 .0 5 )。结论 早期鼻饲生大黄粉能有效防治重症高血压脑出血后并发上消化道出血 ,值得临床推广应用
Objective To study the effect of nasal feeding rhubarb on the prevention and treatment of upper gastrointestinal bleeding after severe hypertensive intracerebral hemorrhage. Methods Eighty-two patients with severe hypertensive intracerebral hemorrhage (GCS) of 8 to 8 years were selected. 41 cases (experimental group) were given nasal feeding rhubarb powder early after onset (24-48 hours), and 41 cases (control group) . All patients with other treatment are basically the same. Results 37 patients with upper gastrointestinal bleeding. The experimental group of 13 cases, 12 cases of upper gastrointestinal bleeding cured, the cure time (7.3 ± 2. 4) d (n = 12); control group of 24 cases, 14 cases of upper gastrointestinal bleeding cured, healing time (13.1 ± 3.2) d (n = 14). The average rate of upper gastrointestinal bleeding and upper gastrointestinal bleeding cured in the experimental group was significantly lower than that in the control group (P <0.05), while the cure rate of upper digestive hemorrhage was significantly higher than that in the control group (P <0.05) . Conclusion Early nasal feeding rhubarb powder can effectively prevent and treat upper gastrointestinal bleeding after severe hypertensive intracerebral hemorrhage and is worthy of clinical application