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1 妇癌化疗中的耐药问题肿瘤多药耐药性 (ＭＤＲ)是当今基础和临床医学研究的热点之一。许多肿瘤常规化疗效果差、预后不良是困扰临床的重要难题 ,而肿瘤多药耐药性则是肿瘤化疗失败的关键因素。有关耐药研究也多 ,现分述如下。1 1 耐药细胞化疗耐药的发生有两种情况 ,一是自
1 Drug Resistance in Chemotherapy of Women With Cancer Multidrug Resistance (MDR) is one of the hot topics in basic and clinical medicine research. The poor efficacy of conventional chemotherapy for many tumors and poor prognosis is an important problem that afflicts the clinic, and multidrug resistance of tumors is a key factor in the failure of cancer chemotherapy. There are many studies on drug resistance, which are now described as follows. 11 There are two situations in which chemotherapy resistance occurs in drug-resistant cells. One is self-