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9例肺癌术前经支气管动脉单次灌注丝裂霉素-C 20mg。灌注后平均10.4天进行手术切除.9例中Ⅱ期6例,Ⅲ期3例。术后标本行光镜和电镜(6例)检查,仅1例显示有较明显的疗效反应。7例随访,平均存活10.1月。本组有限资料说明,术前单次灌注丝裂霉素-C 无济于提高手术的疗效.
Nine patients with lung cancer received a single perfusion of mitomycin C 20 mg before bronchial artery surgery. An average of 10.4 days after perfusion was performed for surgical resection. Of the 9 cases, 6 were in phase II and 3 were in phase III. The specimens were examined by light microscopy and electron microscopy (6 cases). Only 1 case showed obvious response. Seven patients were followed up for an average of 10.1 months. This group of limited data shows that a single preoperative infusion of mitomycin C did not improve the efficacy of surgery.