微量元素对生物的生存,健康和疾病有着非常重要的关系。樊振亚在研究人体转铁蛋白及乳铁蛋白对鼠疫菌生长的影响中,首次将营养免疫的概念应用于人体与鼠疫菌关系的研究,以便更好地解释鼠疫苗使人致病的机理以及鼠疫菌在动物宿主体内保存的机制。本文按照营养免疫概念这一理论,主要研究了黄鼠感染鼠疫菌后,其体内微量元素的变化规律,以探讨某些元素在鼠疫动物病中的作用。 Trace elements have a very important relationship to biological survival, health and disease. Fan Zhenya in the study of human transferrin and lactoferrin on the growth of Y. pestis, the concept of nutritional immunology for the first time applied to the relationship between human and Y. pestis in order to better explain the mechanism of murine vaccine makes human disease and plague The mechanism of bacterial preservation in animal hosts. In this paper, according to the concept of nutrition and immunity, we mainly study the variation rules of trace elements in the body of Chlamydia trachomatis after infecting Yersinia pestis to explore the role of some elements in the epidemic of plague.