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目的统计分析2012-2014年浙江大学医学院附属第一医院就诊患者中HBsAg、HCV、HIV及TP感染情况,了解期间来院患者四种病原体的感染情况,为临床安全提供参考依据。方法回顾性分析2012-2014年我院住院患者血清中HBV、HCV、HIV和TP感染状况。结果 2012年至2014年共统计214 935人次,HBsAg阳性率为13.08%,HCV阳性率为0.51%,HIV阳性率为0.37%,TP阳性率为2.44%。各年份间HBsAg差异有统计学意义(HbsAg:χ2=55.74,P<0.0001;HCV:χ2=2.24,P=0.327;HIV:χ2=2.67,P=0.26;TP:χ2=2.65,P=0.27)。不同性别之间,HBsAg、HIV或TP阳性率差异有统计学意义(HBsAg:χ2=2 680.6,P<0.0001;HCV:χ2=2.69,P=0.101;HIV:χ2=344.3,P<0.0001;TP:χ2=192.4,P<0.0001);不同年龄段之间,HBsAg、HCV、HIV及TP阳性率差异有统计学意义(HbsAg:χ2=3 036.1,P<0.0001;HCV:χ2=59.45,P<0.0001;HIV:χ2=246.06,P<0.0001;TP:χ2=636.80,P<0.0001)。结论开展术前四项检测,有助于及时了解患者情况,明确人群感染情况,对制定感染的预防及治疗措施,避免院内感染的发生具有十分重要的意义。
Objective To analyze the status of HBsAg, HCV, HIV and TP infection in patients attending the First Affiliated Hospital of Zhejiang University from 2012 to 2014, and to understand the infection status of four pathogens in hospital during the period of 2012-2014, providing a reference for clinical safety. Methods The levels of HBV, HCV, HIV and TP in inpatients from 2012 to 2014 in our hospital were analyzed retrospectively. Results From 2012 to 2014, a total of 214 935 individuals were counted. The positive rate of HBsAg was 13.08%, the positive rate of HCV was 0.51%, the positive rate of HIV was 0.37% and the positive rate of TP was 2.44%. There were significant differences in HBsAg between years (HbsAg: χ2 = 55.74, P <0.0001; HCV: χ2 = 2.24, P = 0.327; . The positive rates of HBsAg, HIV or TP were significantly different among different genders (HBsAg: χ2 = 2 680.6, P <0.0001; HCV: χ2 = 2.69, P = 0.101; The positive rates of HBsAg, HCV, HIV and TP were statistically different between different age groups (HbsAg: χ2 = 3 036.1, P <0.0001; HCV: χ2 = 59.45, P < 0.0001; HIV: χ2 = 246.06, P <0.0001; TP: χ2 = 636.80, P <0.0001). Conclusion Carrying out the four preoperative tests will help to keep abreast of the situation of the patients and to clarify the situation of human infection. It is of great significance to formulate the prevention and treatment of infection and avoid the occurrence of nosocomial infection.