随着快节奏生活方式的转变、生活压力的增加，冠状动脉粥样硬化性心脏病（冠心病）发病率日益增长，其对公众健康造成严重的威胁。冠心病的形成过程受多种因素影响，如血脂、血压、凝血功能等。近年来，许多研究显示，亚临床甲状腺功能减退症（亚临床甲减）与冠心病关系密切，亚临床甲减常伴有高脂血症、高凝状态、高同型半胱氨酸血症等，增加冠心病的发病率。通过早期检测甲状腺功能对异常甲状腺功能患者及早干预可一定程度上影响冠心病的发展。“,”The incidence of coronary heart disease (CHD) has been increasing along with the changes of fast-paced lifestyle and increasing life stress.It has become a serious threat to public healthy.The formation of CHD is affected by many factors,such as cholesterol,blood pressure,blood coagulation,et al.In recent years,many studies have shown that subclinical hypothyroidism and CHD are closely related .Subclinical hypothyroidism is usually accompanied by hyperlipidemia, hypercoagulable state, high homocysteine, etc, which increases the incidence of CHD.Early detection of the thyroid function and early intervention to the patients with abnormal thyroid functions can affect the progression of CHD to some extent .Here is to make a review of the possible mechanism of subclinical hypothyroidism and the formation of CHD .