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该试验的目的是为了观察希腊裔的健康肥胖儿童是否在儿童时期就存在X综合征的临床及代谢特点。笔者对25例6-14岁的肥胖儿及18名年龄、性别均与之相匹配的儿童组成的对照组进行了口服葡萄糖耐量试验(OGTT),观察其血糖及血胰岛素水平。通过用数学模型对OGTT的结果进行分析以评估检测对象的胰岛素敏感性及胰岛素抵抗。在禁食1夜后,对体重指数(BMI)、血压、血清脂蛋白和转氨酶浓度进行测定。肥胖儿的血压明显高于对照组(收缩压及舒张压)(P<
The purpose of this trial was to see if healthy, obese Greek children have the clinical and metabolic characteristics of Syndrome X during childhood. Oral glucose tolerance test (OGTT) was conducted in 25 children aged 6-14 years with obesity and 18 age-matched and matched children. The levels of blood glucose and insulin were observed. The results of OGTT were analyzed using mathematical models to assess the insulin sensitivity and insulin resistance of the test subjects. After one night of fasting, body mass index (BMI), blood pressure, serum lipoprotein and aminotransferase concentrations were determined. Obese children’s blood pressure was significantly higher than the control group (systolic and diastolic blood pressure) (P <