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目的 探讨 SARS患者出院 2个月后细胞免疫和体液免疫功能的变化。方法 分别采用流式细胞仪和散射免疫比浊仪检测 31例 SARS出院 2个月患者外周血 T淋巴细胞亚群和免疫球蛋白水平 ,并与正常对照组比较。结果 与对照组相比 ,SARS组 CD3+ 、CD8+ 细胞百分数升高 ,CD4 + 细胞百分数无明显改变 ,CD4 + /CD8+ 比值和 NK细胞百分数下降 ;Ig A水平明显降低 ,Ig G、Ig M、C3、C4水平差异无显著性。结论 SARS患者出院 2个月后仍存在细胞免疫和体液免疫功能的低下。
Objective To investigate the changes of cellular immunity and humoral immune function in SARS patients 2 months after discharge. Methods T lymphocyte subsets and immunoglobulin levels in peripheral blood of 31 SARS patients discharged from hospital for two months were detected by flow cytometry and immunoturbidimetric turbidimetry, respectively, and compared with the normal control group. Results Compared with the control group, the percentages of CD3 + and CD8 + cells in SARS group were increased, the percentages of CD4 + cells did not change significantly, the ratio of CD4 + / CD8 + and the percentage of NK cells decreased; IgA, C4 level difference was not significant. Conclusion SARS patients still have low cellular immunity and humoral immune function 2 months after discharge.