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测定了甲硫脑啡肽对肝损伤小鼠淋巴细胞和巨噬细胞的效应．结果显示肝损伤能够显著地抑制淋巴细胞的增殖反应，甲硫脑啡肽可以减轻这种抑制作用．甲硫脑啡肽也提高肝损伤组淋巴细胞的电泳率，这提示淋巴细胞表面电荷的改变．巨噬细胞移动抑制实验的数据提示甲硫脑啡肽能够显著地抑制巨噬细胞移动抑制因子与巨噬细胞结合．实验结果表明甲硫脑啡肽对免疫细胞功能起重要调节作用．
The effect of met-enkephalin on lymphocytes and macrophages in mice with liver injury was determined. The results show that liver injury can significantly inhibit lymphocyte proliferation response, methotrexate enkephalin can reduce this inhibitory effect. Methamphetamine also increased the rate of lymphocyte lymphocyte electrophoresis in the liver injury group, suggesting a change in the surface charge of lymphocytes. Macrophage migration inhibition data suggest that methionine enkephalin significantly inhibits the binding of macrophage migration inhibitory factor to macrophages. Experimental results show that methyl-thio-enkephalin plays a key regulatory role in immune cell function.