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用抗病毒药联合免疫增强剂对41例单疱病毒性角膜炎患者进行治疗。A 组患者(21例)用无环鸟苷、干扰素和转移因子治疗,B 组患者(20例)用无环鸟苷和干扰素治疗。结果A 组的复发率明显低于B组(P<0.05)。治愈后,A 组的淋巴细胞转化率(LTR)与E-玫瑰花结形成细胞(E-RFC)接近对照组水平(P>0.05),B 组的LTR 与E-RFC 则明显低于对照组与A 组水平(P<0.05)。提示转移因子能降低HSK 的复发率,并能提高HSK 患者的细胞免疫功能。
41 cases of herpes simplex virus keratitis were treated with antiviral agents combined with immune enhancers. Patients in group A (n = 21) were treated with acyclovir, interferon and transfer factor, and patients in group B (n = 20) were treated with acyclovir and interferon. Results The recurrence rate of group A was significantly lower than that of group B (P <0.05). After treatment, LTR and E-RFC in group A were significantly lower than those in control group (P> 0.05), while LTR and E-RFC in group B were significantly lower than those in control group Compared with group A (P <0.05). Tip transfer factor can reduce the recurrence rate of HSK, and can improve cellular immune function in HSK patients.