论文部分内容阅读
测定108对骨龄延迟病例和对照的尿氟、血清铜、钙、镁和锌含量。用EPILOG Plus软件包中条件Logistic回归模型对检测结果进行了单因素、多因素和因素之间一级交互作用分析。结果表明,尿氟和血清铜两个因素是高氟区7～15岁青少年骨龄延迟的危险因素。尿氟含量在316.32～1601.58μmol/L者发生骨龄延迟的危险性是在35.26～78.94μmol/L者的4.95倍。血清铜在13.69～22.82 μmol/L者发生骨龄延迟的危险性是6.61～13.68μmol/L者的4倍。氟与钙对骨龄延迟发生有拮抗作用。铜与钙、镁、锌对骨龄延迟的发生均有协同作用。
Determination of urinary fluoride, serum copper, calcium, magnesium and zinc in 108 cases of delayed bone age and control. The conditional Logistic regression model in the EPILOG Plus software package was used to analyze the test results by single-level, multi-factor and factor-one interaction analysis. The results showed that urinary fluoride and serum copper are two risk factors of delayed bone age in 7 ~ 15-year-old adolescents in high fluoride area. The risk of delayed bone age at 316.32-1601.58 μmol / L was 4.95 times higher among 35.26-78.94 μmol / L. Serum copper in 13.69 ~ 22.82 μmol / L, the risk of delayed bone age was 6.61 ~ 13.68μmol / L 4 times. Fluoride and calcium antagonism of delayed onset of bone age. Copper and calcium, magnesium, zinc have a synergistic effect on the occurrence of delayed bone age.