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报告51例肺炎性假瘤,男33例、女18例,占本院同期临床拟诊为肺癌手术切除472例的10.8％。患者年龄19-66岁,平均44.5岁。随访1-13年,未见复发和转移。病变最大直径1.5-15cm,56％不足4cm,45例边界清楚或有包膜,只6例弥漫与肺组织无分界。镜下,按主要的细胞类型和组织结构分为4型:假乳头状瘤型(33例,64.7％)、纤维组织细胞型(14例,27.5％)、浆细胞肉芽肿型(2例,3.9％)和假性淋巴瘤型(2例,3.9％),但各型之间有广泛的交叉。作者认为,本病属炎症性质,结果造成组织的过量增生。本病鉴别诊断时有困难,尤其当冰冻切片检查时,与间皮瘤区别更为不易,网状纤维染色对鉴别诊断无用。
Reported 51 cases of pneumonia pseudotumor, 33 males and 18 females, accounting for 10.8% of 472 cases of surgical resection of lung cancer. The patient’s age ranged from 19 to 66 years and averaged 44.5 years. Follow-up 1-13 years, no recurrence and metastasis. The maximum diameter of lesions was 1.5-15cm, 56% was less than 4cm, 45 cases had clear boundaries or capsules, and only 6 cases had diffuse and lung tissues without boundaries. Under the microscope, the main cell types and tissue structures were divided into 4 types: pseudopapillary tumor type (33 cases, 64.7%), fibrous tissue cell type (14 cases, 27.5%), plasma cell granulomatous type (2 cases, 3.9%) and pseudo-lymphoma type (2 cases, 3.9%), but there was extensive crossover between types. The authors believe that the disease is of an inflammatory nature, resulting in excessive tissue hyperplasia. The differential diagnosis of this disease is difficult, especially when the frozen section examination is more difficult to distinguish with mesothelioma, reticular fiber staining is not useful for differential diagnosis.