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目的:探讨中药配合肝动脉栓塞化疗(TACE)对肝癌生长的影响。方法:65例行TACF患者随机分为中药组(34例)与对照组(31例),中药组配合化瘀清肝汤加减治疗,观察两组肿瘤生长率变化;并观察39例(中药组21例、对照组18例)治疗后肿瘤标本中增殖细胞核抗原标记指数(PCNALI)、DNA含量(DNAI)、异倍体率(APR)及S期细胞比率(SPF)。结果:中药组月平均肿瘤生长率明显低于对照组(P<0.05),细胞增殖活性指标PCNALI、DNAI、APR及SPF亦明显低于对照组(P<0.05)。结论:化瘀清肝汤配合TACE更有助于抑制肝癌生长。
Objective: To investigate the effect of traditional Chinese medicine combined with transcatheter arterial chemoembolization (TACE) on the growth of hepatocellular carcinoma. Methods: Sixty-five patients with TACF were randomly divided into two groups: the traditional Chinese medicine group (34 cases) and the control group (31 cases). The traditional Chinese medicine group was treated with Huayu qinggan decoction, and the changes of tumor growth rate were observed. 21 cases, and 18 cases of control group), PCNAALI, DNA content, aneuploidy rate and S phase cell ratio (SPF). Results: The average tumor growth rate of Chinese herbal medicine group was significantly lower than that of control group (P <0.05). PCNALI, DNAI, APR and SPF were also significantly lower than those of control group (P <0.05). Conclusion: Huayu Qinggan Decoction with TACE is more helpful to inhibit the growth of liver cancer.