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目的研究经导管动脉化学栓塞(TACE)联合经皮乙酸注射(PAI)治疗原发性肝癌的疗效。资料与方法选择52例肝癌患者,分为TACE联合PAI治疗组和单纯TACE治疗组,比较两组治疗效果。结果联合组与单纯TACE组有效率分别为61.5%、30.8%,两组间差异有统计学意义(P<0.05),1、2年生存率分别为80.8%,61.5%;69.2%,30.8%,差异有统计学意义(P<0.01)。结论与单纯TACE相比,TACE联合PAI治疗中、晚期巨块型肝癌有较好的临床疗效。
Objective To study the efficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous acetic acid injection (PAI) in the treatment of primary liver cancer. Materials and Methods 52 patients with hepatocellular carcinoma were selected and divided into TACE combined with PAI and TACE alone. The effect of treatment was compared between the two groups. Results The effective rates of the combined group and the TACE group were 61.5% and 30.8% respectively. The difference between the two groups was statistically significant (P<0.05). The 1 and 2 year survival rates were 80.8%, 61.5%, 69.2%, and 30.8% respectively. The difference was statistically significant (P<0.01). Conclusion Compared with TACE alone, TACE combined with PAI has good clinical efficacy in the treatment of middle or late stage massive liver cancer.