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目的:探讨非低体重绝经后2型糖尿病女性髋部骨折风险、股骨颈强度综合指数变化及其影响因素。方法:选取非低体重绝经后女性626例，根据2010年美国糖尿病协会糖尿病诊断标准分为2型糖尿病组、糖尿病前期组、非糖尿病组。每位参与者均完成问卷调查、体格检查、实验室检查及双能X线吸收仪(DXA)检查。结果:2型糖尿病组髋部骨折发生率显著高于非糖尿病组(3.4%对0.7%, n P0.05)。腰椎1-4、股骨颈和全髋骨密度2型糖尿病组与非糖尿病组、糖尿病前期组与非糖尿病组相比差异均无统计学意义(n P>0.05)。2型糖尿病组股骨颈强度综合指数显著低于非糖尿病组(n P0.05)。回归分析显示，年龄、体重指数是股骨颈骨密度、股骨颈强度综合指数的主要影响因素(n P0.05). The composite indices of femoral neck strength in T2DM group was significantly lower than that in non-diabetic group(n P0.05). Regression analysis showed that age and body mass index were the main influential factors of the femoral neck bone mineral density and the composite indices of femoral neck strength(n P<0.05).n Conclusion:The composite indices of femoral neck strength could be used as one of the markers to evaluate the risk of hip fracture in type 2 diabetic patients.