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应用透射电镜观察常年性变应性鼻炎（ＰＡＲ）发作期的鼻粘膜肥大细胞，发现肥大细胞颗粒表现为四种形态特征：①高电子密度颗粒；②中等电子密度颗粒；③低电子密度颗粒；④空泡。依所含颗粒的不同，肥大细胞主要表现为三种形态：①脱颗粒前形态；②脱颗粒形态；③空泡形态。本文就肥大细胞及其颗粒的形态学变化与脱颗粒过程的关系进行了讨论。
Transmission electron microscopy was used to observe the nasal mucosal mast cells in perennial allergic rhinitis (PAR) and found that there are four morphological features of mast cells: ① high electron density particles; ② middle electron density particles; ③ low electron density particles; ④ empty bubble. According to the different particles contained, mast cells are mainly manifested in three forms: ① pre-degranulation morphology; ② degranulation morphology; ③ vacuolar morphology. This article discusses the relationship between the morphological changes of mast cells and their granules and the degranulation process.