美国西南医学中心的研究人员最近发现了一种通过靶向KRAS基因治疗肺癌的新途径。KRAS基因是人类癌症中常见的突变基因之一,也是很难成功进行靶向治疗的基因。此前研究表明KRAS基因的编码产物K-Ras会影响细胞分裂,KRAS基因发生突变会导致正常细胞出现增殖失控从而发生癌变。在该研究中研究人员对肺癌中的KRAS进行了研究,发现ACSL3酶介导的KRAS活性对于肺癌细胞存 Researchers at the Southwest Medical Center recently discovered a new way to treat lung cancer by targeting the KRAS gene. The KRAS gene is one of the common mutations in human cancers and is also a difficult gene for successful targeted therapy. Previous studies have shown that KRAS gene encoding product K-Ras will affect cell division, KRAS gene mutation will lead to normal cell proliferation out of control and thus the occurrence of cancer. In this study, researchers studied KRAS in lung cancer and found that ACSL3 enzyme-mediated KRAS activity was negatively correlated with lung cancer cell stock