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瑞典皇家科学院10月10日在瑞典首都斯德哥尔摩宣布,将2001年诺贝尔化学奖奖金的一半授予美国科学家威廉·诺尔斯与日本科学家野依良治,以表彰他们在“手性催化氢化反应”领域所做出的贡献;奖金的另一半授予美国科学家巴里·夏普莱斯,以表彰他在“手性催化氧化反应”领域所取得的成就。许多分子具有两种形态,这两种形态互为镜像,可以比喻成人的左手和右手,故称之为“手性分子”或“手征性分子”。在自然状态下,其中一种镜像形态通常居支配地位。手性分子所具有的两种形态,在毒性等方面往往存在差别。在人体细胞中,手性分子的一种形态可能合适有用,但另一种却可能有害。
The Swedish Royal Academy of Sciences announced in Stockholm, Sweden on October 10 that it awarded half of the 2001 Nobel Prize in Chemistry for the grant to American scientist William Knowles and Japanese scientist Norio Yoshihide in recognition of their commitment to “chiral catalytic hydrogenation” ; The other half of the prize was awarded to American scientist Barry Sharples in recognition of his achievements in the field of “chiral catalytic oxidation”. Many molecules have two forms. The two forms are mirror images of each other. They can be compared to the left hand and the right hand of an adult, so they are called “chiral molecules” or “chiral molecules.” In the natural state, one of the mirror images usually dominates. Chiral molecules have two forms, there are often differences in toxicity and so on. In human cells, one form of a chiral molecule may be suitable, but the other may be harmful.