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矽肺是一种以肺部胶原纤维化为主的进行性疾病,其发病机理学说很多,但均未确切阐明,治疗上亦没有明确的方向。近年来国内外陆续发现了一些对矽肺模型及临床有较好疗效的药物,如 P_(204)及其衍生物,氯喹、磷酸哌喹、磷酸羟基哌喹、氮氧磷酸哌喹、汉防己甲素、千金藤素、轻环藤宁、小蘖胺等双苄基异喹啉类生物碱,铝制剂(如柠檬
Silicosis is a progressive disease characterized mainly by pulmonary fibrosis. Although there are many theories about the pathogenesis of silicosis, none of them has been elucidated clearly and there is no clear direction for its treatment. In recent years, some drugs have been found successively in silicosis model and clinically effective in recent years, such as P 204 and its derivatives, chloroquine, piperaquine phosphate, hydroxyperpene phosphate, piperaquine oxime, tetrandrine Succinctin, cortisone, Cypermethrin, spermidine and other bis-benzyl isoquinoline alkaloids, aluminum preparations (such as lemon