报道了某些金属离子络合物和有机硒化物的合成，并在小鼠上初步评价了它们的辐射防护作用。其中天冬氨酸锌（Ｄ－１）、３，５－二异丙基水杨酸（Ｄ－３）及其铜盐（Ｄ－４）和硒硫辛酸（Ｄ－６）对受到致死剂量照射的小鼠具有一定的防护效果，分别提高活存率４０％、２０％、３０％和４０％。硒取代硫辛酸的一个或两个硫原子后，其抗辐射作用明显减弱，毒性增大。对这一类化合物尚难肯定其辐射防护效果，有待进一步研究． The synthesis of certain metal ion complexes and organic selenides was reported and their radioprotective effects were initially evaluated in mice. The effects of zinc aspartate (D-1), 3,5-diisopropyl salicylic acid (D-3) and copper salts (D-4) and seleno lipoic acid (D-6) Irradiated mice have a protective effect, respectively, to increase the survival rate of 40%, 20%, 30% and 40%. After the selenium replaces one or two sulfur atoms of lipoic acid, the anti-radiation effect is obviously weakened and the toxicity is increased. For this class of compounds is still difficult to confirm its radiation protection effect, pending further study.