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大鼠农药慢性毒性与致癌合并实验是费时最长、参加人员最多、消耗财力和物质最大、操作繁琐复杂而又经不起重复的一个高难度研究工作,对其进行质量控制显得尤为重要。主要包括实验开始前的实验设计质量控制、实验过程中的全程质量控制和实验结束后的资料整理和实验报告质量控制。简言之,就是“确实做好预测,周密设计剂量,精心饲养动物,细心观察反应,认真测定指标,实事求是总结”。
Chronic toxicity and carcinogenicity experiments of pesticides in rats are the most difficult research work that takes the longest time, the largest number of participants, the largest financial and material resources, the complicated operation and the complicated operation, and the quality control is particularly important. Mainly include experimental design before the start of quality control, the whole process of quality control during the experiment and after the end of the data collation and experimental report quality control. In short, it is “really do a good job in predicting, careful design of dose, carefully animal husbandry, careful observation of the reaction, a serious measure of indicators, seek truth from facts ”.