作者指出,患者服用了利福平或广谱抗菌药物,就不宜采用口服避孕药避孕。如患有结核病的妇女,在应用口服避孕药的同时又服用了利福平,因利福平会加速炔雌醇和孕激素的代谢,使其在血液中的浓度显著降低,以致影响避孕效果。在应用口服避孕药的同时又应用四环素、氯霉素、新霉素、氨苄青霉素或呋喃妥英等药物,这些药物会阻碍炔雌醇的再吸收,导 The authors note that patients taking rifampicin or broad-spectrum antibiotics, it is not appropriate to use oral contraceptives contraception. For example, women with tuberculosis who take oral contraceptives while taking rifampin, because rifampin will speed up the metabolism of ethinyl estradiol and progesterone, so that its concentration in the blood significantly reduced, so as to affect the contraceptive effect. In the application of oral contraceptives while the application of tetracycline, chloramphenicol, neomycin, ampicillin or nitrofurantoin and other drugs, these drugs will block the reabsorption of ethinyl estradiol, lead