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以37℃下由表皮葡萄球菌在需氧条件下形成的生物膜为模型,评价了载万古霉素和(或)利福平的纳米脂质体的体外抗菌活性。采用溶剂蒸发法制备载利福平的脂质体,含有万古霉素的脂质体采用脱水-再水化方法制备。所制备的阴离子、阳离
The in vitro antibacterial activity of nano-liposomes containing vancomycin and / or rifampicin was evaluated using a biofilm formed by Staphylococcus epidermidis under aerobic conditions at 37 ° C as a model. Liposomes containing rifampicin were prepared by solvent evaporation. The vancomycin-containing liposomes were prepared by dehydration-rehydration method. The prepared anion is cationic