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目的:了解我院药物不良反应(ADR)发生的特点,促进临床合理用药。方法:对我院收集到的217例ADR报告,按患者年龄、性别、给药途径、ADR程度、药物类型、ADR涉及器官或系统及临床表现等进行分类统计与分析。结果:涉及ADR的药物共有217种,抗微生物类药物居首位,其次为中成药;静脉注射引发的ADR为151例(占69.59%);ADR可发生于人体各个系统,但主要为变态反应,以皮肤及其附件损害最为严重,皮肤反应的ADR为总报告例数的67.74%。结论:临床应重视ADR的报告和监测工作,以减少或避免ADR的发生。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our hospital and to promote rational drug use in clinic. Methods: A total of 217 ADR reports collected in our hospital were classified and analyzed according to patient’s age, sex, route of administration, degree of ADR, type of drug, organ or system and clinical manifestation involved in ADR. Results: A total of 217 drugs were involved in ADR, antimicrobial drugs ranked the first place, followed by proprietary Chinese medicines; ADR caused by intravenous injection was 151 cases (69.59%); ADR can occur in various systems of the human body, but mainly allergic reactions , With the most severe skin and its attachments, the ADR of the skin reaction was 67.74% of the total reported cases. Conclusion: Clinical reports and monitoring of ADR should be emphasized in order to reduce or avoid the occurrence of ADR.