论文部分内容阅读
目的研究阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)与小儿慢性咳嗽之间的关系。方法选取2009年6月至2012年3月在我院检查证实为OSA合并慢性咳嗽的患儿27例,对所有患儿采取手术治疗或持续气道正压通气治疗(CPAP)OSA,用多导睡眠监测仪监测(polysomnograph,PSG)检测患儿睡眠呼吸暂停低通气指数(index of apneahypopnea,AHI)、经皮血氧饱和度(pulse oxygensaturation,SpO2)等。应用咳嗽视觉模拟评分(cough visual analogue scale,VAS)评价小儿慢性咳嗽情况。结果 27例OSA合并慢性咳嗽患儿经手术治疗或CPAP无创通气治疗后,OSA症状均明显好转。AHI治疗前为(75.5±9.3)次/h,治疗后为(4.7±1.3)次/h,差异有统计学意义(P<0.01);VAS评分治疗前为(83.1±10.3分,治疗后为(86.4±10.8)分,差异无统计学意义(P>0.05)。AHI与VAS无明显相关(r=-0.24,P=0.081)。结论治疗小儿OSA对小儿慢性咳嗽没有明显影响。
Objective To investigate the relationship between obstructive sleep apnea (OSA) and chronic cough in children. Methods Twenty-seven children with OSA complicated with chronic cough in our hospital from June 2009 to March 2012 were selected. Surgery or continuous positive airway pressure (CPAP) OSA were performed in all children. Sleep apnea hypopnea index (AHI), and pulse oxygensaturation (SpO2) were measured in children with polysomnograph (PSG). The cough visual analogue scale (VAS) was used to evaluate the chronic cough in children. Results 27 cases of OSA with chronic cough in children undergoing surgery or CPAP non-invasive ventilation, OSA symptoms were significantly improved. AHI was (75.5 ± 9.3) times / h before treatment and (4.7 ± 1.3) times / h after treatment, respectively, the difference was statistically significant (P0.01); before treatment, VAS score was (83.1 ± 10.3) (86.4 ± 10.8), there was no significant difference between the two groups (P> 0.05) .AHI had no significant correlation with VAS (r = -0.24, P = 0.081) .Conclusion The treatment of pediatric OSA has no obvious effect on chronic cough in children.