论文部分内容阅读
目的由于TRUTS可能发生“前带”现象,如果临床仅做单项TRUST,不做TPPA,就会有部分梅毒患者可能漏诊。方法采用梅毒甲苯胺红不加热血清试验(TRUST)和梅毒螺旋体抗体凝集法(TPPA)联合检测门诊病例中的300人次。结果门诊病例300人次中,梅毒急性期患者TRUST阳性滴度可达1:32以上,与TPPA抗体检测均为阳性,符合率100%;治疗后患者,TRUST可转为阴性,转阴率3%,但是TPPA抗体检测仍为阳性。TRUST阴性的患者或TRUST弱阳性可疑反应者,如果TPPA阳性,TRUST需稀释做滴度,从而避免“前带”现象的发生,导致强阳性样本出现假阴性的结果,滴检率5%。结论为了减少漏检,提高诊断率,两试验应同时做,以便及时发现漏检现象。
Objective Because TRUTS may occur before the phenomenon of “with”, if the clinical only single TRUST, do TPPA, there will be some patients may be missed diagnosis of syphilis. Methods 300 outpatients were tested with TRUST and TPPA. Results Out of 300 outpatients, the TRUST-positive titer in patients with acute syphilis was more than 1:32, which was positive with TPPA antibody, and the coincidence rate was 100%. After treatment, TRUST turned negative and the negative conversion rate was 3% , But the TPPA antibody test is still positive. TRUST-negative patients or TRUST weakly-suspicious responders, if the TPPA-positive, TRUST need to be diluted to do the titer in order to avoid “before the band ” phenomenon, resulting in strong positive samples false negative results, the drop detection rate of 5% . Conclusion In order to reduce the missed inspection and improve the diagnostic rate, the two tests should be done at the same time in order to find the missed inspection in time.