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在过去十年中,心律失常的临床处理有了很大的改变。直流电电击法的采用,使大多数类型阵发性心律失常的紧急处理有了革新。然而,心脏电复律术作为一种方法,对预防反复发作性心律失常仅具有限的价值,而且对控制洋地黄过量所引起的心律失常可能具有危险。因此,在心律失常的预防处理中,注意力再次转向抗心律失常药物的选用。不久以前,临床医师仅知道一种类型的抗心律失常药物,即奎尼丁和奎尼丁样化合物,而现在却有很多种抗心律失常药物,虽然对它们的抗心律失常的基本作用方式大多尚不明了。因此,对常用和较新的抗心律失常药物的作用方式进行合理分类,就日益重要。
In the past decade, the clinical management of arrhythmias has changed dramatically. The adoption of DC electric shock has revolutionized the emergency management of most types of paroxysmal arrhythmias. However, cardioversion as a method has only limited value in preventing recurrent arrhythmias and may be at risk for controlling arrhythmias caused by overdose of digitalis. Therefore, in the prevention and treatment of arrhythmia, attention turned back to the selection of antiarrhythmic drugs. Not long ago, clinicians only knew of one type of anti-arrhythmic drug, quinidine and quinidine-like compounds, and now there are many antiarrhythmic drugs, although most of the basic anti-arrhythmic effects on them are unknown It’s Therefore, it is increasingly important to classify the mode of action of commonly used and newer antiarrhythmic drugs.