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1979年11月27日,纳络酮合成及应用鉴定会在上海召开。纳络酮是吗啡类药物的专一性拈抗剂,对脑内抗痛物质也有拮抗作用,为研究针麻原理和脑内神经介质功能的重要工具药物。过去需依赖进口,价格昂贵,影响了针麻原理研究工作的开展。上海第一医学院药学系合成药化教研组以蒂巴因为起始原料,研制成功纳络酮,其物理常数和生物测定数据与国外产品结果一致。在研制过程中,对国外文献作了一定改进,从而提
November 27, 1979, naloxone synthesis and application of identification will be held in Shanghai. Naloxone is a specific antagonist of morphine drugs, and also antagonizes intracerebral anti-inflammatory substances. It is an important tool for studying the principle of acupuncture anesthesia and the function of nerve mediators in the brain. In the past to rely on imports, expensive, affecting the acupuncture anesthesia research work. Shanghai First Medical College Department of Pharmacology and Pharmacology Teaching and Research Group to Tiba as a starting material, the successful development of naloxone, the physical constants and bioassay data consistent with the results of foreign products. In the development process, made some improvements to foreign literature, thereby mentioning