脊索瘤为一少见肿瘤,虽生长缓慢,但结局严酷。它来源于脊索的胚性残余,好发于蝶枕部(35％)和骶尾部(50％),前者一般均有头痛、视力障碍及其他脑神经损害,仅偶尔表现有鼻部症状。Mayo医院近60余年来所诊治的1弱例脊索瘤患者中,1/3发生于颅部,其中8例的初期表现是弃部征状;患者女5,男3;平均38岁(24~51)。主要表现有头痛、单侧鼻阻、流涕、鼻音及鼻妞,3例仅 Chordoma is a rare tumor. Although it grows slowly, the outcome is severe. It originated from the embryonic remnants of the notochord, and it occurs in the occipital peduncle (35%) and the sacrococcygeal end (50%). The former generally have headaches, visual disturbances and other cranial nerve damage, and only occasionally show nasal symptoms. Of the 1 cases of chordomas diagnosed and treated by Mayo Hospital in the past more than 60 years, 1/3 occurred in the cranial region, of which 8 cases had abandonment symptoms at the initial stage; 5 females and 3 males; an average of 38 years old (24~ 51). Mainly manifested as headache, unilateral nasal obstruction, runny nose, nasal sound, and nasal girl, 3 cases only