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目的:探讨不育男性体质量指数(body mass index,BMI)与精液质量间的相关性。方法:选择就诊于本院不育门诊的男性共803名,以中国成人BMI标准将其分为低体质量组(BMI<18.5 kg/m2)、正常组(BMI 18.5~23.9 kg/m2)、超重组(BMI 24.0~27.9 kg/m2)、肥胖组(BMI 28.0~29.9 kg/m2)、重度肥胖组(BMI≥30.0 kg/m2),并按照世界卫生组织第5版标准检测精液质量参数。统计分析不同BMI与性激素水平、精液质量参数之间的关系。结果:肥胖组的E2明显高于非肥胖组(P<0.001);随着BMI等级上升,T水平及T/LH值均逐渐降低(P<0.001)。正常组精液体积显著大于其他各组(P<0.001)。低体质量、正常组与超重组相比,精子总数明显较多(P<0.05)。其余精液质量参数各组间无统计学差异。BMI大小与E2水平呈显著正相关(P<0.001),与T水平、T/LH及精子总数呈显著负相关(均P<0.01)。T/LH与精子总数间也呈显著正相关(P<0.01)。结论:超重及肥胖可能对男性生育能力带来不良影响。
Objective: To investigate the correlation between infertile male body mass index (BMI) and semen quality. Methods: A total of 803 males were selected for inpatient infertility clinic in our hospital. They were divided into low body weight group (BMI <18.5 kg / m2), normal group (BMI 18.5-23.9 kg / m2) (BMI 24.0-27.9 kg / m2), obesity group (BMI 28.0-29.9 kg / m2), and severe obesity group (BMI≥30.0 kg / m2). The semen quality parameters were tested according to the WHO version 5 standard. Statistical analysis of different BMI and sex hormone levels, the relationship between semen quality parameters. Results: The E2 level in obese group was significantly higher than that in non-obese group (P <0.001). As the BMI level increased, T level and T / LH level decreased gradually (P <0.001). Normal group semen volume was significantly greater than the other groups (P <0.001). Low body weight, normal group and overweight group, the total number of sperm was significantly more (P <0.05). The remaining semen quality parameters between groups no significant difference. There was a significant positive correlation between BMI and E2 (P <0.001), negative correlation with T level, T / LH and total number of sperm (all P <0.01). There was also a significant positive correlation between T / LH and sperm count (P <0.01). Conclusion: Overweight and obesity may have adverse effects on male fertility.