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目的观察艾滋病并发复数菌败血症患者临床特征和药物敏感试验结果。方法回顾性分析本院12例艾滋病并发复数菌败血症患者的合并症、炎症指标、预后情况、病原菌分布及药敏结果。结果 12例艾滋病患者有10种合并症,检测血清降钙素原(4.75±9.43)μg/L,仅5例升高,院内感染7例,死亡3例;共检出24株菌株,革兰阴性菌8株(33.3%),多重耐药的大肠埃希菌和肺炎克雷伯菌共6株,产超广谱β-内酰胺酶5株;革兰阳性菌13株(54.2%)以溶血性葡萄球菌和金黄色葡萄球菌多见。结论艾滋病合并复数菌败血症患者合并症多样,病死率高,革兰阴性菌耐药比重大,应积极预防及处理。
Objective To observe the clinical features and drug susceptibility test results of patients with AIDS complicated with multiple sepsis. Methods A retrospective analysis of 12 cases of AIDS in our hospital complicated with sepsis in patients with complications, inflammation, prognosis, distribution and drug susceptibility results of pathogens. Results There were 10 kinds of complications in 12 AIDS patients. Serum procalcitonin (4.75 ± 9.43) μg / L, only 5 cases were elevated, 7 cases were nosocomial infection and 3 died. 24 strains of Gram 8 strains of negative bacteria (33.3%), 6 strains of multidrug-resistant Escherichia coli and Klebsiella pneumoniae, 5 strains of extended-spectrum β-lactamase and 13 strains of Gram-positive bacteria Staphylococcus aureus and Staphylococcus aureus more common. Conclusions Patients with AIDS complicated with multiple bacterial sepsis have various complications, high mortality rate and a large proportion of Gram-negative bacteria. Therefore, they should be actively prevented and treated.