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本文报道了一种测定恶性疟原虫对氯喹敏感性的改良方法。三株恶性疟原虫中,FCR-7/肯尼亚株是从一名多次氯喹预防服药和治疗表现为1级抗性的白人患者分离出的;FCR-8/西非株系从一名在西非旅游时因预防服用氯喹不足而发疟疾的白人患者分离出的;FCN-1/尼日利亚株是从一位访问尼日利亚时未服用氯喹而感染疟疾的尼日利亚妇女分离出的。
This article reports an improved method for the determination of susceptibility to chloroquine by Plasmodium falciparum. Of the three strains of Plasmodium falciparum, FCR-7 / Kenya strain was isolated from a Caucasian patient who had received multiple chloroquine prophylaxis and treatment for grade 1 resistance; the FCR-8 / West Africa strain was isolated from a West African traveler Were isolated from white patients who developed malaria because of insufficient use of chloroquine, and FCN-1 / Nigerian strain isolated from a Nigerian woman who had not been treated for chloroquine and malaria while visiting Nigeria.