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目的观察复方阿嗪米特肠溶片联合依托必利分散片治疗功能性消化不良的疗效。方法将120例功能性消化不良患者随机分为3组:A组,40例,复方阿嗪米特肠溶片,100mg/次,3次/d,餐后立即服用;B组,40例,依托必利分散片,50mg/次,3次/d,餐前半小时;C组,复方阿嗪米特肠溶片,100mg/次,3次/d,餐后立即服用,依托必利分散片,50mg/次,3次/d,餐前半小时。观察治疗2周后,各组治疗前后腹胀,食欲不振的积分变化。结果治疗2周后,C组患者腹胀,食欲不振改善总有效率明显高于A,B组患者,差异有统计学意义(P<0.05),A、B组患者腹胀改善总有效率之间差异无统计学意义(P>0.05)。结论复方阿嗪米特肠溶片联合依托必利分散片能有效地缓解功能性消化不良患者的腹胀、食欲不振症状,两者具有一定的协同作用。
Objective To observe the curative effect of compound azinamid enteric-coated tablets combined with etopride dispersible tablets in the treatment of functional dyspepsia. Methods A total of 120 patients with functional dyspepsia were randomly divided into 3 groups: group A, 40 cases, compound azinamid enteric-coated tablets, 100 mg / time, 3 times / d, immediately after meals; group B, 40 cases, Relying on the benefit of dispersible tablets, 50mg / time, 3 times / d, half an hour before meals; C group, compound azintomide enteric-coated tablets, 100mg / time, 3 times / , 50mg / time, 3 times / d, half an hour before meals. Observed after treatment for 2 weeks, each group before and after treatment of abdominal distension, loss of appetite, integral changes. Results After 2 weeks of treatment, the total effective rate of bloating and loss of appetite in group C was significantly higher than that in group A and B (P <0.05), and the difference was statistically significant between group A and group B No statistical significance (P> 0.05). Conclusions The combination of alizarin amiodar enteric-coated tablets and etopride dispersible tablets can effectively relieve bloating and loss of appetite in patients with functional dyspepsia, both of which have some synergistic effects.