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以组织学及组织化学定量分析方法，检测４～７月龄胎儿真皮组织中结缔组织纤维、血管数、多糖及核酸量的动态变化，结果表明：真皮中胶原纤维及弹性纤维的面积百分比随月龄的增大而增高；血管计数及多糖、核酸的平均光密度值均于孕６月组达最大值。提示：真皮的发育和分化与月龄和循环系统的发育关系密切，孕５月前较为缓慢，孕６月后进入加速和完善阶段。
The dynamic changes of connective tissue fibers, blood vessels, polysaccharides and nucleic acids in fetal dermal tissue from 4 to 7 months were detected by histological and histochemical quantitative analysis. The results showed that the area percentages of collagen fibers and elastic fibers in dermis were The age increased and increased; the blood vessel count and the average optical density of polysaccharides and nucleic acids reached the maximum in the first trimester of pregnancy. Tip: dermal development and differentiation and age and the development of the circulatory system are closely linked, pregnant before 5 months more slowly, pregnant June after entering the acceleration and improvement stage.