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目的:观察血浆置换联合中药治疗慢性乙型重型肝炎的疗效。方法:88例患者随机分为治疗组和对照组,对照组采用血浆置换及西药药物治疗,治疗组在对照组基础上加用中药汤剂及大黄煎液灌肠。观察二组患者临床症状、肝功能、凝血酶原时间、凝血酶原活动度、存活率及并发症。结果:治疗组在上述指标的改善上优于对照组(P<0.05);治疗组患者并发症少,死亡率低,明显优于对照组(P<0.05)。结论:血浆置换联合中药能提高慢性乙型重型肝炎的疗效,减少并发症,降低病死率。
Objective: To observe the effect of plasma exchange combined with traditional Chinese medicine in the treatment of chronic severe hepatitis B Methods: Eighty-eight patients were randomly divided into treatment group and control group. The control group was treated with plasma exchange and western medicine. The treatment group was treated with Chinese medicine decoction and rhubarb decoction enema on the basis of the control group. Clinical symptoms, liver function, prothrombin time, prothrombin activity, survival rate and complications of the two groups were observed. Results: The treatment group was better than the control group in improving the above indexes (P <0.05). The treatment group had fewer complications and lower mortality rate, which was significantly better than the control group (P <0.05). Conclusion: Plasma exchange combined with traditional Chinese medicine can improve the efficacy of chronic severe hepatitis B, reduce complications and reduce mortality.