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由二硝基甲苯(DNT)合成4-甲基-1,3-苯撑二氨基甲酸二乙酯(DEMPDC)的反应产物中可能存在以下副产物:2-甲基-5-硝基苯基氨基甲酸乙酯(EMNPC)、3-硝基-4-甲基苯基氨基甲酸乙酯(ENMPC)、2-氨基-4-硝基甲苯(ANT)、2-硝基-4-氨基甲苯(NAT)。这些副产物和DNT及DEMPDC等六个组分或具有不同的功能团,或互成位置异构体,极性相差较大。本文极导这些组分的高效液相色谱分析结果,考查了不同类型色谱柱和流动相组成对分离的影响,并获得适用于定量的标准曲线。
The following by-products may be present in the reaction product of dinitrotoluene (DNT) for the synthesis of diethyl 4-methyl-1,3-phenylenediimidate (DEMPDC): 2-methyl-5-nitrophenyl (EMNPC), 3-nitro-4-methylphenyl urethane (ENMPC), 2-amino-4- nitrotoluene (ANT), 2-nitro- 4-aminotoluene NAT). These by-products and DNT and DEMPDC six components or have different functional groups, or inter-positional isomers, polar differences between the larger. In this paper, the polar components of the HPLC analysis of these components to examine the different types of columns and the mobile phase composition of the separation, and to obtain a quantitative standard curve.