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目的探讨宫颈癌患者术后发生感染相关因素进行临床研究,以发现宫颈癌术后发生感染的危险因素,为临床的相关治疗提供参考依据,减少宫颈癌患者手术感染。方法选取医院2010年12月-2012年12月收治的120例宫颈癌患者的临床资料进行回顾性分析,观察患者相关感染发生情况,并对发生感染的患者的临床资料进行单因素和多因素logistic回归分析,所有数据均采用SPSS 17.0软件分析。结果 120例患者发生感染42例,感染率为35.00%;对42例的临床资料进行单因素分析发现,患者的年龄、宫颈癌的分期、>3种基础疾病、侵入性操作、接受化疗、住院时间以及术后抗菌药物的使用等是引发感染的危险因素,差异有统计学意义(P<0.05);对有统计学意义的单因素进行多因素logistic回归分析发现,患者的年龄、宫颈癌分期、侵入性操作、糖尿病、接受化疗以及抗菌药物的滥用是导致患者术后发生感染的独立危险因素,差异有统计学意义(P<0.05)。结论宫颈癌患者手术后发生感染的危险因素较多,其中患者的年龄、宫颈癌分期、侵入性操作、糖尿病、接受化疗以及抗菌药物的滥用是导致患者术后发生感染的独立危险因素,临床医师需要引起重视并加强预防。
Objective To investigate the clinical factors related to postoperative infection in patients with cervical cancer and find out the risk factors of postoperative infection of cervical cancer so as to provide reference for the clinical treatment and reduce the surgical infection of cervical cancer patients. Methods Clinical data of 120 patients with cervical cancer admitted from December 2010 to December 2012 in our hospital were retrospectively analyzed. The incidence of infection was observed. The clinical data of patients with infection were analyzed by single factor and multivariate logistic Regression analysis, all data were analyzed using SPSS 17.0 software. Results In 120 cases, 42 cases were infected and the infection rate was 35.00%. Univariate analysis of 42 cases showed that age, cervical cancer stage,> 3 kinds of underlying diseases, invasive procedures, chemotherapy, hospitalization Time and the use of antimicrobial agents were the risk factors of infection, the difference was statistically significant (P <0.05); multivariate logistic regression analysis of statistically significant single factor found that the patient’s age, cervical cancer staging , Invasive procedures, diabetes mellitus, chemotherapy and abuse of antimicrobial agents were independent risk factors for postoperative infection. The difference was statistically significant (P <0.05). Conclusion There are many risk factors for infection after operation in patients with cervical cancer. Among them, the age, cervical cancer staging, invasive procedures, diabetes, chemotherapy and the abuse of antibiotics are the independent risk factors of postoperative infection. It needs to be emphasized and prevention strengthened.