无论何种原因导致的终末期肾脏疾病,其肾组织学改变常常具有某些共性,以至难以据此对其原发病作出诊断。事实上,各种慢性肾脏疾病在发展成为肾功能衰竭的进程中,都具有一些共同的机理。终末期肾脏病形态学的变化只是不同病因殊途同归的后果。通常表现为肾小球内细胞外基质的大量堆 Regardless of the cause of end-stage renal disease, renal histological changes often have some common, so difficult to diagnose the underlying disease. In fact, all kinds of chronic kidney diseases have some common mechanisms in their progression to renal failure. Changes in the morphology of end-stage renal disease is only the result of different causes of different purposes. Often manifested as a large number of extracellular matrix glomerular heap